Induction of a Mucosal Cytotoxic T-Lymphocyte Response by Intrarectal Immunization with a Replication-Deficient Recombinant Vaccinia Virus Expressing Human Immunodeficiency Virus 89.6 Envelope Protein

To improve the safety of recombinant vaccinia virus vaccines, modified vaccinia virus Ankara (MVA) has been employed, because it has a replication defect in most mammalian cells. Here we apply MVA to human immunodeficiency virus type 1 (HIV-1) vaccine development by incorporating the envelope protei...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Belyakov, Igor M., Wyatt, Linda S., Ahlers, Jeffrey D., Earl, Patricia, Pendleton, C. David, Kelsall, Brian L., Strober, Warren, Moss, Bernard, Berzofsky, Jay A.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Materias:	Viral Pathogenesis and Immunity
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.8264-8272.1998
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