Induction of a Mucosal Cytotoxic T-Lymphocyte Response by Intrarectal Immunization with a Replication-Deficient Recombinant Vaccinia Virus Expressing Human Immunodeficiency Virus 89.6 Envelope Protein

To improve the safety of recombinant vaccinia virus vaccines, modified vaccinia virus Ankara (MVA) has been employed, because it has a replication defect in most mammalian cells. Here we apply MVA to human immunodeficiency virus type 1 (HIV-1) vaccine development by incorporating the envelope protei...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Belyakov, Igor M., Wyatt, Linda S., Ahlers, Jeffrey D., Earl, Patricia, Pendleton, C. David, Kelsall, Brian L., Strober, Warren, Moss, Bernard, Berzofsky, Jay A.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1998
Matèries:	Viral Pathogenesis and Immunity
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.8264-8272.1998
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