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Induction of a Mucosal Cytotoxic T-Lymphocyte Response by Intrarectal Immunization with a Replication-Deficient Recombinant Vaccinia Virus Expressing Human Immunodeficiency Virus 89.6 Envelope Protein

To improve the safety of recombinant vaccinia virus vaccines, modified vaccinia virus Ankara (MVA) has been employed, because it has a replication defect in most mammalian cells. Here we apply MVA to human immunodeficiency virus type 1 (HIV-1) vaccine development by incorporating the envelope protei...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Belyakov, Igor M., Wyatt, Linda S., Ahlers, Jeffrey D., Earl, Patricia, Pendleton, C. David, Kelsall, Brian L., Strober, Warren, Moss, Bernard, Berzofsky, Jay A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110185/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733870/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.8264-8272.1998
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