Interleukin (IL)-21-independent pathogen-specific CD8(+) T-cell expansion, and IL-21-dependent suppression of CD4(+) T-cell IL-17 production

Although interleukin-21 (IL-21) potently activates and controls the differentiation of immune cells after stimulation in vitro, the role for this pleiotropic cytokine during in vivo infection remains poorly defined. Herein, the requirement for IL-21 in innate and adaptive host defence after Listeria...

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Main Authors: Ertelt, James M, Johanns, Tanner M, Rowe, Jared H, Way, Sing Sing
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967264/
https://ncbi.nlm.nih.gov/pubmed/20465570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03287.x
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