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PDL-1 blockade impedes T cell expansion and protective immunity primed by attenuated Listeria monocytogenes

Infection with attenuated Listeria monocytogenes (Lm) is a robust in vivo model for examining how antigen-specific T cells are primed, and subsequent challenge with virulent Lm allows for the protective effects of T cell priming to be quantified. Herein, we investigated the role of PDL-1 in T cell p...

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Main Authors: Rowe, Jared H., Johanns, Tanner M., Ertelt, James M., Way, Sing Sing
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677094/
https://ncbi.nlm.nih.gov/pubmed/18490756
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