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Autoreactive Th1 cells activate monocytes to support regional Th17 responses in inflammatory arthritis
We have examined mechanisms underlying the formation of pathologic Th17 cells using a transgenic mouse model in which autoreactive CD4(+) T cells recognize influenza virus hemagglutinin (HA) as a ubiquitously expressed self-antigen, and induce inflammatory arthritis. The lymph nodes of arthritic mic...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3608750/ https://ncbi.nlm.nih.gov/pubmed/23420889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203212 |
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