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A Receptor Tyrosine Kinase Network Composed of Fibroblast Growth Factor Receptors, Epidermal Growth Factor Receptor, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, and Hepatocyte Growth Factor Receptor Drives Growth and Survival of Head and Neck Squamous Carcinoma Cell Lines

Our laboratory has previously shown that some gefitinib-insensitive head and neck squamous cell carcinoma (HNSCC) cell lines exhibit dominant autocrine fibroblast growth factor receptor (FGFR) signaling. Herein, we deployed a whole-genome loss-of-function screen to identify genes whose knockdown pot...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Singleton, Katherine R., Kim, Jihye, Hinz, Trista K., Marek, Lindsay A., Casás-Selves, Matias, Hatheway, Clark, Tan, Aik Choon, DeGregori, James, Heasley, Lynn E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Pharmacology and Experimental Therapeutics 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608435/
https://ncbi.nlm.nih.gov/pubmed/23371912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.084111
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