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Aurora-A kinase (AURKA) in normal and pathological cell growth

Temporally and spatially controlled activation of the Aurora-A kinase (AURKA) is regulates centrosome maturation, entry into mitosis, formation and function of the bipolar spindle, and cytokinesis. Genetic amplification, and mRNA and protein overexpression of Aurora-A are common in many types of sol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nikonova, Anna S., Astsaturov, Igor, Serebriiskii, Ilya G., Dunbrack, Roland L., Golemis, Erica A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607959/
https://ncbi.nlm.nih.gov/pubmed/22864622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1073-7
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