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Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis
The centrosomal Aurora-A kinase (AURKA) regulates mitotic progression, and overexpression and hyperactivation of AURKA commonly promotes genomic instability in many tumors. Although most studies of AURKA focus on its role in mitosis, some recent work identified unexpected nonmitotic activities of AU...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3395655/ https://ncbi.nlm.nih.gov/pubmed/22621899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-12-1056 |
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