Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis

The centrosomal Aurora-A kinase (AURKA) regulates mitotic progression, and overexpression and hyperactivation of AURKA commonly promotes genomic instability in many tumors. Although most studies of AURKA focus on its role in mitosis, some recent work identified unexpected nonmitotic activities of AU...

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Bibliographic Details
Main Authors: Plotnikova, Olga V., Nikonova, Anna S., Loskutov, Yuri V., Kozyulina, Polina Y., Pugacheva, Elena N., Golemis, Erica A.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395655/
https://ncbi.nlm.nih.gov/pubmed/22621899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-12-1056
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