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Rapid calcium-dependent activation of Aurora-A kinase

Oncogenic hyperactivation of the mitotic kinase Aurora-A (AurA) in cancer is associated with genomic instability. Increasing evidence indicates that AurA also regulates critical processes in normal interphase cells, but the source of such activity has been obscure. We report here that multiple stimu...

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Autors principals: Plotnikova, Olga V., Pugacheva, Elena N., Dunbrack, Roland L., Golemis, Erica A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963827/
https://ncbi.nlm.nih.gov/pubmed/20842194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1061
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