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Rapid calcium-dependent activation of Aurora-A kinase

Oncogenic hyperactivation of the mitotic kinase Aurora-A (AurA) in cancer is associated with genomic instability. Increasing evidence indicates that AurA also regulates critical processes in normal interphase cells, but the source of such activity has been obscure. We report here that multiple stimu...

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Detalhes bibliográficos
Main Authors: Plotnikova, Olga V., Pugacheva, Elena N., Dunbrack, Roland L., Golemis, Erica A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963827/
https://ncbi.nlm.nih.gov/pubmed/20842194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1061
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