A new class of isothiocyanate-based irreversible inhibitors of Macrophage Migration Inhibitory Factor (MIF)

Macrophage migration inhibitory factor (MIF) is a homotrimeric multifunctional proinflammatory cytokine that has been implicated in the pathogenesis of several inflammatory and autoimmune diseases. Current therapeutic strategies for targeting MIF focus on developing inhibitors of its tautomerase act...

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Autors principals: Ouertatani-Sakouhi, Hajer, El-Turk, Farah, Fauvet, Bruno, Roger, Thierry, Le Roy, Didier, Karpinar, Damla Pinar, Leng, Lin, Bucala, Richard, Zweckstetter, Markus, Calandra, Thierry, Lashuel, Hilal A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607106/
https://ncbi.nlm.nih.gov/pubmed/19737008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900957e
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