A new class of isothiocyanate-based irreversible inhibitors of Macrophage Migration Inhibitory Factor (MIF)

Macrophage migration inhibitory factor (MIF) is a homotrimeric multifunctional proinflammatory cytokine that has been implicated in the pathogenesis of several inflammatory and autoimmune diseases. Current therapeutic strategies for targeting MIF focus on developing inhibitors of its tautomerase act...

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Bibliografski detalji
Glavni autori: Ouertatani-Sakouhi, Hajer, El-Turk, Farah, Fauvet, Bruno, Roger, Thierry, Le Roy, Didier, Karpinar, Damla Pinar, Leng, Lin, Bucala, Richard, Zweckstetter, Markus, Calandra, Thierry, Lashuel, Hilal A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607106/
https://ncbi.nlm.nih.gov/pubmed/19737008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900957e
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