Expression and function of macrophage migration inhibitory factor (MIF) in melioidosis.

Macrophage migration inhibitory factor (MIF) has emerged as a pivotal mediator of innate immunity and has been shown to be an important effector molecule in severe sepsis. Melioidosis, caused by Burkholderia pseudomallei, is an important cause of community-acquired sepsis in Southeast-Asia. We aimed...

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Main Authors: W Joost Wiersinga, Thierry Calandra, Liesbeth M Kager, Gerritje J W van der Windt, Thierry Roger, Didier le Roy, Sandrine Florquin, Sharon J Peacock, Fred C G J Sweep, Tom van der Poll
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-02-01
Colecção:PLoS Neglected Tropical Diseases
Acesso em linha:http://europepmc.org/articles/PMC2821910?pdf=render
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