Osteopontin Impairs Host Defense during Established Gram-Negative Sepsis Caused by Burkholderia pseudomallei (Melioidosis)

BACKGROUND: Melioidosis, caused by infection with Burkholderia (B.) pseudomallei, is a severe illness that is endemic in Southeast Asia. Osteopontin (OPN) is a phosphorylated glycoprotein that is involved in several immune responses including induction of T-helper 1 cytokines and recruitment of infl...

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Detalhes bibliográficos
Main Authors: van der Windt, Gerritje J. W., Wiersinga, W. Joost, Wieland, Catharina W., Tjia, Ivo C. S. I., Day, Nicholas P., Peacock, Sharon J., Florquin, Sandrine, van der Poll, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930856/
https://ncbi.nlm.nih.gov/pubmed/20824216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000806
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