Toll-Like Receptor 2 Impairs Host Defense in Gram-Negative Sepsis Caused by Burkholderia pseudomallei (Melioidosis)

BACKGROUND: Toll-like receptors (TLRs) are essential in host defense against pathogens by virtue of their capacity to detect microbes and initiate the immune response. TLR2 is seen as the most important receptor for gram-positive bacteria, while TLR4 is regarded as the gram-negative TLR. Melioidosis...

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書誌詳細
主要な著者: Wiersinga, W. Joost, Wieland, Catharina W, Dessing, Mark C, Chantratita, Narisara, Cheng, Allen C, Limmathurotsakul, Direk, Chierakul, Wirongrong, Leendertse, Masja, Florquin, Sandrine, de Vos, Alex F, White, Nicholas, Dondorp, Arjen M, Day, Nicholas P, Peacock, Sharon J, van der Poll, Tom
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2007
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950213/
https://ncbi.nlm.nih.gov/pubmed/17676990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040248
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