Identification and Characterization of Novel Classes of Macrophage Migration Inhibitory Factor (MIF) Inhibitors with Distinct Mechanisms of Action

Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine, is considered an attractive therapeutic target in multiple inflammatory and autoimmune disorders. In addition to its known biologic activities, MIF can also function as a tautomerase. Several small molecules have been reported...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ouertatani-Sakouhi, Hajer, El-Turk, Farah, Fauvet, Bruno, Cho, Min-Kyu, Pinar Karpinar, Damla, Le Roy, Didier, Dewor, Manfred, Roger, Thierry, Bernhagen, Jürgen, Calandra, Thierry, Zweckstetter, Markus, Lashuel, Hilal A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924096/
https://ncbi.nlm.nih.gov/pubmed/20516071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113951
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky