Laddar...
NMR-based functional profiling of RASopathies and oncogenic RAS mutations
Defects in the RAS small G protein or its associated network of regulatory proteins that disrupt GTPase cycling are a major cause of cancer and developmental RASopathy disorders. Lack of robust functional assays has been a major hurdle in RAS pathway-targeted drug development. We used NMR to obtain...
Sparad:
| Huvudupphovsmän: | , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2013
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607025/ https://ncbi.nlm.nih.gov/pubmed/23487764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218173110 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|