A carregar...
NMR-based functional profiling of RASopathies and oncogenic RAS mutations
Defects in the RAS small G protein or its associated network of regulatory proteins that disrupt GTPase cycling are a major cause of cancer and developmental RASopathy disorders. Lack of robust functional assays has been a major hurdle in RAS pathway-targeted drug development. We used NMR to obtain...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607025/ https://ncbi.nlm.nih.gov/pubmed/23487764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218173110 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|