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Aminosalicylic Acid Inhibits IκB Kinase α Phosphorylation of IκBα in Mouse Intestinal Epithelial Cells

Tumor necrosis factor α (TNFα)-stimulated nuclear factor (NF) κB activation plays a key role in the pathogenesis of inflammatory bowel disease (IBD). Phosphorylation of NFκB inhibitory protein (IκB) leading to its degradation and NFκB activation, is regulated by the multimeric IκB kinase complex, in...

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Detalhes bibliográficos
Main Authors: Yan, Fang, Polk, D. Brent
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606885/
https://ncbi.nlm.nih.gov/pubmed/10029619
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