A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer

Caspases are important regulators and executioners in the apoptosis pathways and play crucial roles in carcinogenesis. We tested the hypothesis that functional variants of CASP genes are associated with risk of squamous cell carcinoma of the head and neck (SCCHN) and second primary malignancy (SPM)....

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Guan, Xiaoxiang, Liu, Zhensheng, Liu, Hongliang, Yu, Hongping, Wang, Li-E, Sturgis, Erich M., Li, Guojun, Wei, Qingyi
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2013
Sujets:
Research Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606531/
https://ncbi.nlm.nih.gov/pubmed/23271051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-223420
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