A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer

Caspases are important regulators and executioners in the apoptosis pathways and play crucial roles in carcinogenesis. We tested the hypothesis that functional variants of CASP genes are associated with risk of squamous cell carcinoma of the head and neck (SCCHN) and second primary malignancy (SPM)....

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Detalhes bibliográficos
Main Authors: Guan, Xiaoxiang, Liu, Zhensheng, Liu, Hongliang, Yu, Hongping, Wang, Li-E, Sturgis, Erich M., Li, Guojun, Wei, Qingyi
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606531/
https://ncbi.nlm.nih.gov/pubmed/23271051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-223420
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