A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer

Caspases are important regulators and executioners in the apoptosis pathways and play crucial roles in carcinogenesis. We tested the hypothesis that functional variants of CASP genes are associated with risk of squamous cell carcinoma of the head and neck (SCCHN) and second primary malignancy (SPM)....

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Hlavní autoři: Guan, Xiaoxiang, Liu, Zhensheng, Liu, Hongliang, Yu, Hongping, Wang, Li-E, Sturgis, Erich M., Li, Guojun, Wei, Qingyi
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2013
Témata:
Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606531/
https://ncbi.nlm.nih.gov/pubmed/23271051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-223420
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