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Genetic polymorphisms of p21 and risk of second primary malignancy in patients with index squamous cell carcinoma of the head and neck

p21 plays an important role in modulating cell cycle control, inducing apoptosis, and inhibiting cell growth, subsequently affecting cancer risk. We investigated the association between two putatively functional single-nucleotide polymorphisms (SNPs) of p21 (p21 C98A and p21 C70T) among 1282 patient...

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Detalhes bibliográficos
Main Authors: Lei, Dapeng, Sturgis, Erich M., Liu, Zhensheng, Zafereo, Mark E., Wei, Qingyi, Li, Guojun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812571/
https://ncbi.nlm.nih.gov/pubmed/19955391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp279
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