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Glutathione S-transferase polymorphisms and risk of second primary malignancy after index squamous cell carcinoma of the head and neck

PURPOSE: Glutathione S-transferases (GSTs) detoxify carcinogens in tobacco smoke, which plays a major role not only in development of squamous cell carcinoma of the head and neck (SCCHN) but also second primary malignancy (SPM) after index SCCHN. EXPERIMENTAL DESIGN: We hypothesized that GSTM1 null,...

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Detalhes bibliográficos
Main Authors: Zafereo, Mark E., Sturgis, Erich M., Aleem, Sal, Chaung, Katrina, Wei, Qingyi, Li, Guojun
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698715/
https://ncbi.nlm.nih.gov/pubmed/19401526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-08-0222
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