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Association of p53 codon 72 polymorphism with risk of second primary malignancy in patients with squamous cell carcinoma of the head and neck
BACKGROUND: p53 plays a critical role in cellular anti-cancer mechanisms, and has been correlated with second primary malignancy (SPM) development. A common polymorphism in codon 72 of the p53 results in an amino acid substitution and could influence p53 function. We hypothesized that p53 codon 72 p...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864328/ https://ncbi.nlm.nih.gov/pubmed/20225330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25072 |
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