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Association of p53 codon 72 polymorphism with risk of second primary malignancy in patients with squamous cell carcinoma of the head and neck

BACKGROUND: p53 plays a critical role in cellular anti-cancer mechanisms, and has been correlated with second primary malignancy (SPM) development. A common polymorphism in codon 72 of the p53 results in an amino acid substitution and could influence p53 function. We hypothesized that p53 codon 72 p...

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Bibliografische gegevens
Hoofdauteurs: Li, Fanglin, Sturgis, Erich M, Chen, Xingming, Zafereo, Mark E., Wei, Qingyi, Li, Guojun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864328/
https://ncbi.nlm.nih.gov/pubmed/20225330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25072
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