Genetic variants of p27 and p21 as predictors for risk of second primary malignancy in patients with index squamous cell carcinoma of head and neck

BACKGROUND: Cell cycle deregulation is common in human cancer, and alterations of p27 and p21, two critical cell cycle regulators, have been implicated in the development of many human malignancies. Therefore, we hypothesize that p27 T109G polymorphism individually or in combination with p21 (C98A a...

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Detalhes bibliográficos
Main Authors: Wang, Zhongqiu, Sturgis, Erich M, Zhang, Fenghua, Lei, Dapeng, Liu, Zhensheng, Xu, Li, Song, Xicheng, Wei, Qingyi, Li, Guojun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331801/
https://ncbi.nlm.nih.gov/pubmed/22449259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-17
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