Genetic variants of p27 and p21 as predictors for risk of second primary malignancy in patients with index squamous cell carcinoma of head and neck

BACKGROUND: Cell cycle deregulation is common in human cancer, and alterations of p27 and p21, two critical cell cycle regulators, have been implicated in the development of many human malignancies. Therefore, we hypothesize that p27 T109G polymorphism individually or in combination with p21 (C98A a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Wang, Zhongqiu, Sturgis, Erich M, Zhang, Fenghua, Lei, Dapeng, Liu, Zhensheng, Xu, Li, Song, Xicheng, Wei, Qingyi, Li, Guojun
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2012
נושאים:
Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331801/
https://ncbi.nlm.nih.gov/pubmed/22449259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-17
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