Genetic variants in p53-related genes confer susceptibility to second primary malignancy in patients with index squamous cell carcinoma of head and neck

Because of their important roles in mediating the stabilization and expression of p53, we hypothesized that high-risk genotypes of polymorphisms in p53-related genes, including p53, p73, p14(ARF), MDM2 and MDM4, may be associated with an increased risk of second primary malignancy (SPM) after index...

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Main Authors: Jin, Lei, Sturgis, Erich M., Zhang, Yang, Huang, Zhigang, Wei, Peng, Guo, Wei, Wang, Zhongqiu, Wei, Qingyi, Song, Xicheng, Li, Guojun
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697893/
https://ncbi.nlm.nih.gov/pubmed/23508638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt096
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