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Rgs13 Constrains Early B Cell Responses and Limits Germinal Center Sizes
Germinal centers (GCs) are microanatomic structures that develop in secondary lymphoid organs in response to antigenic stimulation. Within GCs B cells clonally expand and their immunoglobulin genes undergo class switch recombination and somatic hypermutation. Transcriptional profiling has identified...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606317/ https://ncbi.nlm.nih.gov/pubmed/23533672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060139 |
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