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Biased S1PR1 Signaling in B cells Subverts Responses to Homeostatic Chemokines Severely Disorganizing Lymphoid Organ Architecture
Ligand engaged chemoattractant receptors trigger Gα(i) subunit nucleotide exchange stimulating the activation of downstream effector molecules. Activated chemoattractant receptors also dock G-protein-coupled receptor kinases (GRKs) that help mediate receptor desensitization. Here, we show that the B...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6814389/ https://ncbi.nlm.nih.gov/pubmed/31548329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900678 |
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