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Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines
We report that infection of draining lymph nodes (DLNs) by Salmonella typhimurium results in the specific downregulation of the homeostatic chemokines CCL21 and CXCL13, which are essential for normal DLN organization and function. Our data reveal that the mechanism of this suppression is dependent o...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616497/ https://ncbi.nlm.nih.gov/pubmed/19855398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2036 |
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