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Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes
Granules of mast cells (MCs) enhance adaptive immunity when, on activation, they are released as stable particles. Here we show that submicrometre particles modelled after MC granules augment immunity when used as adjuvants in vaccines. The synthetic particles, which consist of a carbohydrate backbo...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3749235/ https://ncbi.nlm.nih.gov/pubmed/22266469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3222 |
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