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Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes

Granules of mast cells (MCs) enhance adaptive immunity when, on activation, they are released as stable particles. Here we show that submicrometre particles modelled after MC granules augment immunity when used as adjuvants in vaccines. The synthetic particles, which consist of a carbohydrate backbo...

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Bibliografske podrobnosti
Main Authors: St. John, Ashley L., Chan, Cheryl Y., Staats, Herman F., Leong, Kam W., Abraham, Soman N.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749235/
https://ncbi.nlm.nih.gov/pubmed/22266469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3222
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