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Variations in Gnai2 and Rgs1 Expression Affect Chemokine Receptor Signaling and the Organization of Secondary Lymphoid Organs

Ligand bound chemoattractant receptors activate the heterotrimeric G protein Gi to stimulate downstream signaling pathways to properly position lymphocytes in lymphoid organs. Here we show how variations the expression of a chemokine receptor and in two components in the signaling pathway, Gα(i2) an...

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Detalhes bibliográficos
Main Authors: Hwang, II-Young, Park, Chung, Harrision, Kathleen, Huang, Ning-Na, Kehrl, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908210/
https://ncbi.nlm.nih.gov/pubmed/20508603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2010.27
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