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Normal thymocyte egress, T cell trafficking, and CD4(+) T cell homeostasis require interactions between RGS proteins and Gα(i2)
Adaptive immunity depends upon mature thymocytes leaving the thymus to enter the bloodstream and the trafficking of T cells through lymphoid organs. Both of these requires heterotrimeric Gα(i) protein signaling, whose intensity and duration are controlled by RGS proteins. Here, we show that RGS prot...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5360501/ https://ncbi.nlm.nih.gov/pubmed/28235863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601433 |
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