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Effect of presenilins in the apoptosis of thymocytes and homeostasis of CD8(+) T cells
Many studies have positioned Notch signaling at various critical junctions during T-cell development. There is, however, debate regarding the role of Notch in the CD4 versus CD8 lineage commitment. Because there are 4 Notch receptors and RBP-Jκ–independent Notch signaling has been reported, we decid...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200904/ https://ncbi.nlm.nih.gov/pubmed/17626841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-070359 |
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