Thymic Atrophy and Apoptosis of CD4(+)CD8(+) Thymocytes in the Cuprizone Model of Multiple Sclerosis

Previous studies on the degenerative animal model of multiple sclerosis suggested that the copper-chelator cuprizone might directly suppress T-cell functions. Peripheral T-cell function in the cuprizone model has already been explored; therefore, in the present study, we investigated, for the first...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Solti, Izabella, Kvell, Krisztian, Talaber, Gergely, Veto, Sara, Acs, Peter, Gallyas, Ferenc, Illes, Zsolt, Fekete, Katalin, Zalan, Petra, Szanto, Arpad, Bognar, Zita
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460035/
https://ncbi.nlm.nih.gov/pubmed/26053248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129217
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