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Thymic Atrophy and Apoptosis of CD4(+)CD8(+) Thymocytes in the Cuprizone Model of Multiple Sclerosis
Previous studies on the degenerative animal model of multiple sclerosis suggested that the copper-chelator cuprizone might directly suppress T-cell functions. Peripheral T-cell function in the cuprizone model has already been explored; therefore, in the present study, we investigated, for the first...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460035/ https://ncbi.nlm.nih.gov/pubmed/26053248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129217 |
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