Amiodarone’s major metabolite, desethylamiodarone inhibits proliferation of B16-F10 melanoma cells and limits lung metastasis formation in an in vivo experimental model

Previously, we demonstrated the in vitro anti-tumor effects of desethylamiodarone (DEA) in bladder and cervix cancer cell lines. In the present study, we intended to establish its potentiality in B16-F10 metastatic melanoma cells in vitro and in vivo. We assessed cell proliferation, apoptosis and ce...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Bognar, Zita, Cseh, Anna Maria, Fekete, Katalin, Antus, Csenge, Bognar, Rita, Tapodi, Antal, Ramadan, Fadi H. J., Sumegi, Balazs, Gallyas, Ferenc
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518930/
https://ncbi.nlm.nih.gov/pubmed/32977329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239088
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