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Involvement of Mitochondrial Mechanisms in the Cytostatic Effect of Desethylamiodarone in B16F10 Melanoma Cells

Previously, we showed that desethylamiodarone (DEA), a major metabolite of the widely used antiarrhythmic drug amiodarone, has direct mitochondrial effects. We hypothesized that these effects account for its observed cytotoxic properties and ability to limit in vivo metastasis. Accordingly, we exami...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Ramadan, Fadi H. J., Szabo, Aliz, Kovacs, Dominika, Takatsy, Aniko, Bognar, Rita, Gallyas, Ferenc, Bognar, Zita
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582344/
https://ncbi.nlm.nih.gov/pubmed/33027919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197346
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