Involvement of Mitochondrial Mechanisms in the Cytostatic Effect of Desethylamiodarone in B16F10 Melanoma Cells

Previously, we showed that desethylamiodarone (DEA), a major metabolite of the widely used antiarrhythmic drug amiodarone, has direct mitochondrial effects. We hypothesized that these effects account for its observed cytotoxic properties and ability to limit in vivo metastasis. Accordingly, we exami...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Ramadan, Fadi H. J., Szabo, Aliz, Kovacs, Dominika, Takatsy, Aniko, Bognar, Rita, Gallyas, Ferenc, Bognar, Zita
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7582344/
https://ncbi.nlm.nih.gov/pubmed/33027919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21197346
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