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Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death
Oligodendrocyte loss and demyelination are major pathological hallmarks of multiple sclerosis. In pattern III lesions, inflammation is minor in the early stages, and oligodendrocyte apoptosis prevails, which appears to be mediated at least in part through mitochondrial injury. Here, we demonstrate p...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964508/ https://ncbi.nlm.nih.gov/pubmed/20157013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp337 |
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