Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death

Oligodendrocyte loss and demyelination are major pathological hallmarks of multiple sclerosis. In pattern III lesions, inflammation is minor in the early stages, and oligodendrocyte apoptosis prevails, which appears to be mediated at least in part through mitochondrial injury. Here, we demonstrate p...

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Bibliografiske detaljer
Main Authors: Veto, Sara, Acs, Peter, Bauer, Jan, Lassmann, Hans, Berente, Zoltan, Setalo, Gyorgy, Borgulya, Gabor, Sumegi, Balazs, Komoly, Samuel, Gallyas, Ferenc, Illes, Zsolt
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964508/
https://ncbi.nlm.nih.gov/pubmed/20157013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp337
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