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An Essential Role for RGS Protein/Gα(i2) Interactions in B Lymphocyte Directed Cell Migration and Trafficking
Chemokines engage B lymphocyte surface receptors triggering heterotrimeric G-protein Gα(i) subunit guanine nucleotide exchange. RGS proteins limit the duration that Gα(i) subunits remain GTP bound, and the loss of an individual RGS protein typically enhances chemokine receptor signaling. Here, we sh...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4339488/ https://ncbi.nlm.nih.gov/pubmed/25617475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401952 |
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