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Gα(i) Signaling Promotes Marginal Zone B Cell Development by Enabling Transitional B Cell ADAM10 Expression
The follicular (FO) versus marginal zone (MZ) B cell fate decision in the spleen depends upon BCR, BAFF, and Notch2 signaling. Whether or how G(i) signaling affects this fate decision is unknown. Here, we show that direct contact with Notch ligand expressing stromal cells (OP9-Delta-like 1) cannot p...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5904254/ https://ncbi.nlm.nih.gov/pubmed/29696016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00687 |
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