An Essential Role for RGS Protein/Gα(i2) Interactions in B Lymphocyte Directed Cell Migration and Trafficking

Chemokines engage B lymphocyte surface receptors triggering heterotrimeric G-protein Gα(i) subunit guanine nucleotide exchange. RGS proteins limit the duration that Gα(i) subunits remain GTP bound, and the loss of an individual RGS protein typically enhances chemokine receptor signaling. Here, we sh...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Hwang, Il-Young, Park, Chung, Harrison, Kathleen, Boularan, Cedric, Galés, Céline, Kehrl, John H.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339488/
https://ncbi.nlm.nih.gov/pubmed/25617475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401952
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