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Rgs13 Constrains Early B Cell Responses and Limits Germinal Center Sizes

Germinal centers (GCs) are microanatomic structures that develop in secondary lymphoid organs in response to antigenic stimulation. Within GCs B cells clonally expand and their immunoglobulin genes undergo class switch recombination and somatic hypermutation. Transcriptional profiling has identified...

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Detalhes bibliográficos
Main Authors: Hwang, Il-Young, Hwang, Kyung-Sun, Park, Chung, Harrison, Kathleen A., Kehrl, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606317/
https://ncbi.nlm.nih.gov/pubmed/23533672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060139
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