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Acquisition of the metastatic phenotype is accompanied by H(2)O(2)-dependent activation of the p130Cas signaling complex

Reactive Oxygen Species (ROS) have emerged as cellular signaling molecules and are implicated in metastatic disease by their ability to drive invasion and migration. Here we define the signaling adaptor protein p130Cas as a key redox-responsive molecular trigger that is engaged in highly invasive me...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Hempel, Nadine, Bartling, Toni R., Mian, Badar, Melendez, J. Andres
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606285/
https://ncbi.nlm.nih.gov/pubmed/23345605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0478
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