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Redox Control of the Senescence Regulator Interleukin-1α and the Secretory Phenotype
Senescent cells accumulate in aged tissue and are causally linked to age-associated tissue degeneration. These non-dividing, metabolically active cells are highly secretory and alter tissue homeostasis, creating an environment conducive to metastatic disease progression. IL-1α is a key senescence-as...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820855/ https://ncbi.nlm.nih.gov/pubmed/24062309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493841 |
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