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Acquisition of the metastatic phenotype is accompanied by H(2)O(2)-dependent activation of the p130Cas signaling complex
Reactive Oxygen Species (ROS) have emerged as cellular signaling molecules and are implicated in metastatic disease by their ability to drive invasion and migration. Here we define the signaling adaptor protein p130Cas as a key redox-responsive molecular trigger that is engaged in highly invasive me...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606285/ https://ncbi.nlm.nih.gov/pubmed/23345605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0478 |
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