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Crystallization of the SH2-binding site of p130Cas in complex with Lck, a Src-family kinase

Cas-family proteins serve as docking proteins in integrin-mediated signal transduction. The founding member of this family, p130Cas, becomes tyrosine-phosphorylated in response to extracellular stimuli such as integrin-mediated cell adhesion and ligand engagement of receptor tyrosine kinases. Cas pr...

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Bibliografische gegevens
Hoofdauteurs: Nasertorabi, Fariborz, Alonso, Andres, Rogers, Scott W., Mustelin, Tomas, Vuori, Kristiina, Liljas, Lars, Ely, Kathryn R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: International Union of Crystallography 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952266/
https://ncbi.nlm.nih.gov/pubmed/16510985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309104034177
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