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Crystallization of the SH2-binding site of p130Cas in complex with Lck, a Src-family kinase
Cas-family proteins serve as docking proteins in integrin-mediated signal transduction. The founding member of this family, p130Cas, becomes tyrosine-phosphorylated in response to extracellular stimuli such as integrin-mediated cell adhesion and ligand engagement of receptor tyrosine kinases. Cas pr...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
International Union of Crystallography
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1952266/ https://ncbi.nlm.nih.gov/pubmed/16510985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309104034177 |
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